Steve Borthwick has named his first squad as England head coach and it includes recalls for Nick Isiekwe of St Albans and former Saffron Walden junior Max Malins.
The duo, who once played for Old Albanian as well, will be part of a 36-strong training camp next week.
Ex-pupils of Harpenden St George's, and former juniors at Harpenden Rugby Club, Maro Itoje and Owen Farrell are also included.
There will also be five uncapped players - Fin Smith, Ollie Hassell-Collins, George McGuigan, Cadan Murley and Jack Walker.
England start their campaign with the Calcutta Cup fixture against Scotland on February 4 and the new gaffer is chomping at the bit to get going.
Borthwick said: "This is an exciting squad with a blend of Six Nations experience and young talent, and includes players who are in excellent form in the Premiership.
"We are all looking forward to the challenges of the Six Nations and we will approach this great tournament with a spirit of courage and total commitment.
"I know the players can't wait to get back to Twickenham and give our fans a performance they can be proud of.
"The hard work for the Scotland game starts now."
England squad in full ahead of 2023 Six Nations
FORWARDS
Ollie Chessum (Leicester Tigers, 5 caps)
Dan Cole (Leicester Tigers, 95 caps)
Ben Curry (Sale Sharks,1 cap)
Alex Dombrandt (Harlequins, 9 caps)
Ben Earl (Saracens, 13 caps)
Ellis Genge (Bristol Bears, 43 caps)
Jamie George (Saracens, 72 caps)
Joe Heyes (Leicester Tigers, 7 caps)
Jonny Hill (Sale Sharks, 19 caps)
Nick Isiekwe (Saracens, 8 caps)
Maro Itoje (Saracens, 62 caps)
Courtney Lawes (Northampton Saints, 96 caps)
Lewis Ludlam (Northampton Saints, 14 caps)
George McGuigan (Gloucester Rugby, uncapped)
Bevan Rodd (Sale Sharks, 2 caps)
Sam Simmonds (Exeter Chiefs, 18 caps)
Kyle Sinckler (Bristol Bears, 56 caps)
Mako Vunipola (Saracens, 74 caps)
Jack Walker (Harlequins, uncapped)
Jack Willis (Toulouse, 6 caps)
BACKS
Elliot Daly (Saracens, 57 caps)
Owen Farrell (Saracens, 101 caps)
Tommy Freeman (Northampton Saints, 3 caps)
Ollie Hassell-Collins (London Irish, uncapped)
Dan Kelly (Leicester Tigers, 1 cap)
Max Malins (Saracens, 14 caps)
Joe Marchant (Harlequins, 13 caps)
Alex Mitchell (Northampton Saints, 1 cap)
Cadan Murley (Harlequins, uncapped)
Henry Slade (Exeter Chiefs, 52 caps)
Fin Smith (Northampton Saints, uncapped)
Marcus Smith (Harlequins, 17 caps)
Freddie Steward (Leicester Tigers, 17 caps)
Manu Tuilagi (Sale Sharks, 50 caps)
Jack van Poortvliet (Leicester Tigers, 7 caps)
Ben Youngs (Leicester Tigers, 121 caps)
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